Mirasorvone: A masked 20-keptopregnane from the defensive secretion of a diving beetle (Thermonectus mamoratus).
The sunburst diving beetle, Thermonectus marmoratus, ejects a milky fluid fromits prothoracic defensive glands when disturbed. Two major volatile components of this secretion are steroids; cybisterone (structure 7) constitutes about 20% of the volatiles, and a new steroid, mirasorvone, about 50%. Mi...
| Main Authors: | , , , , , , , , , |
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| Format: | |
| Language: | English |
| Published: |
1997
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| Online Access: | http://ezproxy.villanova.edu/login?url=https://digital.library.villanova.edu/Item/vudl:177266 |
| Summary: | The sunburst diving beetle, Thermonectus
marmoratus, ejects a milky fluid fromits prothoracic defensive
glands when disturbed. Two major volatile components of this
secretion are steroids; cybisterone (structure 7) constitutes
about 20% of the volatiles, and a new steroid, mirasorvone,
about 50%. Mirasorvone is assigned an 18-oxygenated pregnane
structure (structure 9) on the basis of extensive spectroscopic
data. Although no 18-oxygenated steroid has been
described previously from an insect source, a closely related
hormone with mineralocorticoid activity, 18-hydroxydeoxycorticosterone
(structure 13), has been isolated from the
adrenal glands of rats. |
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