Integration of behavior and timing: Anatomically separate systems for distributed processing?.
Discusses the basic components of an interval timer and describes how these components may be realized in the brain. To this end, the authors present electrophysiological data showing duration-specific activity in the striatum and discuss the implications these data carry for current and future models of interval timing. The chapter outlines the logical possibility that interval timing in the brain might not be composed of independent, serial mechanisms, but rather operate via feedback loops in which the output of an internal clock serves to dynamically modify its own input. It is argued that reference to a generalized timing model incorporating both input and output processes could provide guidance in the search for the neural mechanisms of timing because such processes likely play an important part in the production of a temporal percept. Data are presented showing that striatal neurons can indicate times of expected reward through fluctuations in their firing rates, thereby suggesting a prominent role of the striatum in timing and time perception. Thus, it may be possible that the output of individual striatal neurons serves as a decision stage function of an interval timer.
|Main Author:||Matell, Matthew.|
|Other Authors:||Meck, Warren., Nicolelis, Miguel.|