CD4+ T Cells Mature in the Absence of MHC Class I and Class II Expression in Ly-6A.2 Transgenic Mice.

The TCRs expressed on T lymphocytes recognize foreign peptides bound to MHC molecules. This reactivity is the basis of specific immune response to the foreign Ag. How such specificities are generated in the thymus is still being debated. Signals generated through TCR upon interaction with self MHC-p...

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Bibliographic Details
Main Authors: Henderson, S. Christine., Berezovskaya, Alla., English, Andrea., Palliser, Deborah., Rock, Kenneth L., Bamezai, Anil.
Format: Villanova Faculty Authorship
Language:English
Published: 1998
Online Access:http://ezproxy.villanova.edu/login?url=https://digital.library.villanova.edu/Item/vudl:173998